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Cervical Cancer Exposomics and the Impact of Environmental and Lifestyle Factors on Carcinogenesis

Cervical Cancer Exposomics and the Impact of Environmental and Lifestyle Factors on Carcinogenesis
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Author(s): S. Athinarayanan (Sri Ramakrishna Mission Vidyalaya College of Arts and Science, India), K. Dhanakodi (Sri Ramakrishna Mission Vidyalaya College of Arts and Science, India), R. Kavitha (Vel Tech High Tech Dr. Rangarajan Dr. Sakunthala Engineering College, India), M. Robinson Joel (KCG College of Technology, India), S. Athinarayanan (Vel Tech Rangarajan Dr.Sagunthala R&D Institute of Science and Technology, India), A.T. Rajamanickam (Sri Ramakrishna Mission Vidyalaya College of Arts and Science, India), A. Sanjaygandhi (Sri Ramakrishna Mission Vidyalaya College of Arts and Science, India)and S. Muthukumar (PSN College of Engineering and Technology, India)
Copyright: 2026
Pages: 30
Source title: Environmental Factors in Carcinogenesis: Exposome-Driven Insights Into Cancer Risk and Prevention
Source Author(s)/Editor(s): Ramya Raghavan (Sri Sathya Sai University for Human Excellence, India)
DOI: 10.4018/979-8-3373-5796-6.ch002

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Abstract

Cervical cancer remains a significant public health concern, particularly in low- and middle-income countries. While human papillomavirus (HPV) infection is a well-established primary cause, emerging research highlights the role of environmental exposures, lifestyle factors, and socioeconomic conditions in modulating carcinogenesis. This chapter explores the concept of cancer exposomics in the context of cervical cancer, emphasizing the cumulative impact of chemical pollutants, dietary habits, occupational hazards, and lifestyle factors on disease progression. The interplay between HPV infection, environmental toxins (such as endocrine disruptors and heavy metals), and immune system modulation is discussed. Additionally, the chapter highlights the significance of early screening, vaccination, and personalized interventions in mitigating the risk. By integrating exposomic research with molecular epidemiology, this study provides insights into novel preventive and therapeutic strategies for cervical cancer management.

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