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Introduction to Exposome in Gametogenesis Teratogenesis and Cancer

Introduction to Exposome in Gametogenesis Teratogenesis and Cancer
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Author(s): Christopher Oloruntoba Akintayo (Achievers University, Nigeria), Samuel O. Onyekweli (Lagos University Teaching Hospital, Idi-Araba, Nigeria), Gloria Osayamen Omoruyi (Obafemi Awolowo University Teaching Hospital Complex, Nigeria), Tobi O. Olaleye (Achievers University, Nigeria), Oluwakemi M. Olowomeye (Achievers University, Nigeria), Victor O. Osundele (Osun State Ministry of Health, Nigeria)and Paul A. Oyewole (Obafemi Awolowo University Teaching Hospital Complex, Nigeria)
Copyright: 2026
Pages: 106
Source title: Environmental Factors in Carcinogenesis: Exposome-Driven Insights Into Cancer Risk and Prevention
Source Author(s)/Editor(s): Ramya Raghavan (Sri Sathya Sai University for Human Excellence, India)
DOI: 10.4018/979-8-3373-5796-6.ch001

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Abstract

Risk factors provides a chance to comprehend the cancer formation, and its molecular classification. The exposome represents a thorough evaluation of all environmental factors that affect a person throughout their life, including biological, research has demonstrated the connection between adverse developmental outcomes, including growth restriction, preterm birth, and morphological and functional abnormalities, and environmental chemical exposures for both the mother and the father prior to, during, and following conception. According to recent studies, human pregnancy and development can be significantly impacted by environmental exposures to chemical, biological, and physical variables that both the mother and the father experience. Exposures associated with poor developmental outcomes include metals, volatile and persistent organics, chemicals in food, occupational exposures, agricultural chemicals, and pollution of the air and water. Premature birth, mortality, growth restriction, and structural and functional abnormalities are developmental endpoints linked to these exposures.

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