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Toxicogenomics and Pharmacogenomics Research in Health Disparities

Toxicogenomics and Pharmacogenomics Research in Health Disparities
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Author(s): Surendra Prakash Gupta (Shri Vaishnav Vidhyapeeth Viswavidhayalaya, India)and Ankur Bhardwaj (Shri Vaishnav Vidhyapeeth Vishwavidyalaya, India)
Copyright: 2026
Pages: 28
Source title: Environmental Factors in Carcinogenesis: Exposome-Driven Insights Into Cancer Risk and Prevention
Source Author(s)/Editor(s): Ramya Raghavan (Sri Sathya Sai University for Human Excellence, India)
DOI: 10.4018/979-8-3373-5796-6.ch006

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Abstract

In recent years, the fields of toxicogenomics and pharmacogenomics have become increasingly popular as scientists attempt to understand the intricate interactions between genetic variables, environmental exposures, and how these factors affect health outcomes like the onset of diseases and the efficacy of medical treatments. This method has grown in significance for comprehending and resolving health inequalities. Significant racial and ethnic differences in drug response are revealed by combining genetic ancestry and pharmacogenomic data, which can help address health disparities and guide personalized medicine. These fields leverage genetic data to tailor medical treatments, aiming to reduce adverse drug reactions and improve therapeutic efficacy. Understanding these mechanisms are crucial to developing more personalized and effective treatments that account for individual genetic differences and their impact on how people respond to medications. The important developments in the field of omics to comprehend and reduce health disparities are covered in this chapter.

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