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Synthetic Approaches and Medicinal Attributes of Benzotriazoles
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Author(s): Amol Arjun Nagargoje (K.M.C. College, Khopoli, India), Sharad Pandit Panchgalle (K.M.C. College, Khopoli, India), Mubarak Hanif Shaikh (Radhabai Kale Mahila Mahavidyalaya, Ahmednagar, India)and Bapurao B. Shingate (Dr. Babasaheb Ambedkar Marathwada University, India)
Copyright: 2025
Pages: 56
Source title:
Five Membered Bioactive N and O-Heterocycles: Models and Medical Applications
Source Author(s)/Editor(s): Shrikaant Kulkarni (Sanjivani University, India & Victorian Institute of Technology, Australia), Hemantkumar Akolkar (Rayat Shikshan Sanstha’s Abasaheb Marathe Arts and New Commerce Science College, India), Bapurao B. Shingate (Dr. Babasaheb Ambedkar Marathwada University, India)and Vijay M. Khedkar (Vishwakarma University, India)
DOI: 10.4018/979-8-3693-7267-8.ch009
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Abstract
Benzotriazole represents a vital scaffold in the design of new pharmacologically active compounds. Its diverse biological activities and the potential for structural modification make it a promising candidate for future drug development endeavours. Continued research into its synthesis and SAR will further enhance its therapeutic potential. This chapter aims to provide a comprehensive overview of benzotriazole, focusing on its synthesis, biological activities, and potential applications in drug design. By exploring the historical development, modern synthetic methods, and the diverse biological activities of benzotriazole and its derivatives, we will highlight its significance in medicinal chemistry. The environmental and safety aspects of benzotriazole are also discussed, emphasizing the importance of sustainable and safe practices in its use and development.
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