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Supramolecular Approaches to Green Drug Delivery
Abstract
In the pharmaceutical sciences, developing efficient, sustainable, and biocompatible drug delivery systems is crucial. Traditional methods face issues such as poor solubility and low bioavailability. Supramolecular chemistry, which involves the formation of complex structures through noncovalent interactions, offers solutions to these challenges. This chapter discusses the use of supramolecular systems for green drug delivery, aiming to enhance efficacy, specificity, and sustainability. The authors examined how these structures can improve drug solubility, target specificity, and controlled release, reducing environmental impact. This chapter covers fundamental supramolecular chemistry principles; the various structures, such as cyclodextrins, dendrimers, and micelles and their drug delivery applications. This chapter concludes with the future prospects of supramolecular approaches in green drug delivery, highlighting ongoing research, challenges, and directions such as integrating nanotechnology and personalized medicine for better drug delivery systems.
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