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Supramolecules as Efficient Tools for Modern Targeted Drug Delivery Approaches

Supramolecules as Efficient Tools for Modern Targeted Drug Delivery Approaches
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Author(s): Nikita Patel (Krishna School of Science, KPGU, India), Miral Vora (Krishna School of Science, KPGU, India), Asha Joshi (Krishna School of Science, KPGU, India)and Bhupesh Bhatt (Sardar Patel University, India)
Copyright: 2026
Pages: 36
Source title: Demystifying the Complexities of Supramolecular Systems: Real World Applications
Source Author(s)/Editor(s): Keyur D. Bhatt (Ganpat University, India)
DOI: 10.4018/979-8-3693-2774-6.ch003

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Abstract

The field of supramolecular chemistry includes dynamic covalent chemistry as well as the investigation of all forms of intermolecular non-covalent bond formation in engineered molecular systems. Reversible non-covalent interactions, a key component of supramolecular chemistry, include hydrogen-bonding, π-π stacking, hydrophobic, van der Waals, and electrostatic interactions. Advances in supramolecular chemistry in recent times have largely aided biomedical applications. For an understanding of how pharmaceuticals interact with binding sites in biological systems, supramolecular chemistry is crucial. Therapeutic compounds should be momentarily contained within the carrier vehicles and released at a predetermined location or time in order to create effective drug delivery systems (DDS). This chapter summarizes the current trends and notable developments in supramolecular systems with specific functions, along with their many biomedical uses in drug delivery, gene transfection, protein delivery, molecular recognition, and biomimetic chemistry.

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