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Synthetic Strategies and Biomedical Applications of Tetrazoles
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Author(s): H. S. Lalithamba (Siddaganga Institute of Technology, Tumakuru, India), G. K. Prashanth (Sir M. Visvesvaraya Institute of Technology, India), Aisha Siddekha (Government First Grade College, India), M. Ramya (REVA University, Bangalore, India)and G. Nagendra (REVA University, Bangalore, India)
Copyright: 2025
Pages: 36
Source title:
Five Membered Bioactive N and O-Heterocycles: Models and Medical Applications
Source Author(s)/Editor(s): Shrikaant Kulkarni (Sanjivani University, India & Victorian Institute of Technology, Australia), Hemantkumar Akolkar (Rayat Shikshan Sanstha’s Abasaheb Marathe Arts and New Commerce Science College, India), Bapurao B. Shingate (Dr. Babasaheb Ambedkar Marathwada University, India)and Vijay M. Khedkar (Vishwakarma University, India)
DOI: 10.4018/979-8-3693-7267-8.ch010
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Abstract
The present chapter Tetrazoles: synthetic strategies and Biomedical applications reveals different synthetic protocols for the preparation of tetrazoles. A standard aside, nitrile condensation route to metal-catalyzed condensation route, including the greener approaches and ionic liquid mediated approaches were discussed further these tetrazoles are considered on bio isosteres of carboxylic and found various applications in pharma and medicine and exhibit catalytic activities in organic Synthesis. Various methods limit the role of NaN3 and emissions the alternate protocol for the construction of tetrazole. Tetrazole alone and in conjunction with the organic groups including heterocycles exhibit various pharmacological activities that were covered in the chapter. Finally, the chapter allows a reader to choose the best possible pathway to construct the tetrazole ring and provides all necessary references.
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