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Bioactive Pyrazoles: Structure, Function, and Pharmaceutical Potential
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Author(s): Aditi Boruah (Gauhati University, India), Ariful Islam (Gauhati University, India)and Pranjal K. Baruah (Gauhati University, India)
Copyright: 2025
Pages: 48
Source title:
Five Membered Bioactive N and O-Heterocycles: Models and Medical Applications
Source Author(s)/Editor(s): Shrikaant Kulkarni (Sanjivani University, India & Victorian Institute of Technology, Australia), Hemantkumar Akolkar (Rayat Shikshan Sanstha’s Abasaheb Marathe Arts and New Commerce Science College, India), Bapurao B. Shingate (Dr. Babasaheb Ambedkar Marathwada University, India)and Vijay M. Khedkar (Vishwakarma University, India)
DOI: 10.4018/979-8-3693-7267-8.ch002
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Abstract
This chapter discusses about bioactive pyrazoles, which have garnered substantial attention in medicinal chemistry and drug development. Pyrazoles are five-membered heterocyclic compounds characterized by a nitrogen-rich structure, imparting them with unique physicochemical and biological and making them useful for treating various diseases. The chapter explores the synthesis, structural diversity, and functional modifications of pyrazoles that enhance their bioactivity. Detailed discussions highlight the mechanisms of action and therapeutic potential of pyrazole derivatives in various pharmacological areas, including anti-inflammatory, anticancer, antimicrobial, antiviral, neuroprotective, and other applications. The chapter also looks at the latest research and advancements in pyrazole chemistry, including new ways to make them and studies on how their structure affects their activity. By exploring the many uses of bioactive pyrazoles, this chapter shows their importance in contemporary medicinal chemistry in developing new and better medicines.
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