The IRMA Community
Newsletters
Research IRM
Click a keyword to search titles using our InfoSci-OnDemand powered search:
|
CRISPR-Cas9 Technology for Unlocking Immunity Against Infectious Pathogens
|
|
Author(s): M. Suriya (Vels Institute of Science, Technology, and Advanced Studies, India), V. Aarthi (Vels Institute of Science, Technology, and Advanced Studies, India), S. S. Meenambiga (Vels Institute of Science, Technology, and Advanced Studies, India), P. Prakash (Sathyabama Institute of Science and Technology, India)and P. Vivek (Vels Institute of Science, Technology, and Advanced Studies, India)
Copyright: 2026
Pages: 34
Source title:
CRISPR-Cas9 Technology for Precision Medicine
Source Author(s)/Editor(s): Jen-Tsung Chen (National University of Kaohsiung, Taiwan)
DOI: 10.4018/979-8-3373-4857-5.ch003
Purchase
|
Abstract
The development of CRISPR-Cas9 has dramatically changed the field of genome engineering and its utilization in epigenome editing could have profound implications for precision medicine.This ability to precisely target epigenetic marks, including DNA methylation, histone modifications, and chromatin remodeling, allows for exciting therapeutic developments in cancer, neurodegenerative and autoimmune diseases. New developments such as CRISPRi, CRISPRa, and reversible CRISPR off/CRISPR on, allow for complex and multiplexed epigenetic reprogramming with improved specificity and safety. Nonetheless, there are some challenges to delivery off-target effects, stability of epigenetic modification, and moral lines, especially with inheritable epigenetic modification. The essential principles of CRISPR-Cas9-based epigenome editing, its therapeutic prospects for personalized medicine, and the consideration of technological, ethical, and policy aspects associated with epigenome editing are discussed
Related Content
|
Kazi Asraf Ali, Rideb Chakraborty, Naureen Afrose, Chowdhury Mobaswar Hossain, Amit Kotal, Sourav Samanta.
© 2026.
34 pages.
|
|
V. N. Pallavi, Savitha Chowdareddy, Bhumika Iranna Byalahunasishetter, Ramya Raghavan.
© 2026.
38 pages.
|
|
M. Suriya, V. Aarthi, S. S. Meenambiga, P. Prakash, P. Vivek.
© 2026.
34 pages.
|
|
Kumar Ebenezar Kesavarao, Manoj Mani, Mokesh Kadhirvel, Balaji Esakkimuthu, Akilandeswari Govindraj, Jerline Babu Maria, Velayuthaprabhu Shanmugam, Vijaya Anand Arumugam.
© 2026.
40 pages.
|
|
Ajay Sharma, Pratibha Singh.
© 2026.
28 pages.
|
|
Arthi Gunasekaran, Muthupandi Vanaraj, Maria Sneha Philip Kumar, Abidharini Jothi Dheivasikamani, Arthi Boro, Antony Prabhu Jeyabal Philomenathan, Alwin Robert Asirvatham, Vijaya Anand Arumugam.
© 2026.
34 pages.
|
|
Saloua Mabsor-Zgandaoui, Khawla Rachmoune, Soumia Ed-Day.
© 2026.
30 pages.
|
|
|