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Borderline Ovarian Tumors: What Is the Optimal Therapeutic Strategy?
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Author(s): George Pados (1st Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece & Unit for Endoscopic Surgery, Interbalkan Medical Center, Thessaloniki, Greece)and Dimitrios Zouzoulas (1st Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece)
Copyright: 2021
Pages: 17
Source title:
Handbook of Research on Oncological and Endoscopical Dilemmas in Modern Gynecological Clinical Practice
Source Author(s)/Editor(s): Konstantinos Dinas (2nd Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece), Stamatios Petousis (2nd Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece), Matthias Kalder (Department of Obstetrics and Gynaecology, Philipps-University of Marburg, Germany)and George Mavromatidis (2nd Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece)
DOI: 10.4018/978-1-7998-4213-2.ch016
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Abstract
Borderline ovarian tumors (BOTs) are a specific subgroup of ovarian tumors and are characterized by cell proliferation and nuclear atypia without invasion or stromal invasion. They are usually more present in younger people than the invasive ovarian cancer and are diagnosed at an early stage and thus have a better prognosis. Histologically, borderline tumors are divided into serous (50%), mucosal (46%), and mixed (4%). The serous tumors are bilateral in 30% of the cases and are accompanied by infiltrations outside the ovary in 35% of the cases. These infiltrations may be non-invasive or invasive depending on their microscopic appearance and may affect treatment. Surgery is the approach of choice, and laparoscopic surgery, with the undeniable advantages it offers today, is the “gold standard.” All the surgical steps required to properly treat borderline tumors, at both diagnostic and therapeutic levels, can be safely and successfully be applied laparoscopically. Manipulations during surgery should be limited, and biopsies for rapid biopsy should be done within an endoscopic bag.
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