The IRMA Community
Newsletters
Research IRM
Click a keyword to search titles using our InfoSci-OnDemand powered search:
|
Bioactive Five-Membered Heterocycles With Two Heteroatoms Fused With a Benzene Ring (a) Benzimidazole
|
|
Author(s): Paran Jyoti Borpatra (Institute of Science, Banaras Hindu University, India)and Mintu Maan Dutta (Arya Vidyapeeth College, India)
Copyright: 2025
Pages: 62
Source title:
Five Membered Bioactive N and O-Heterocycles: Models and Medical Applications
Source Author(s)/Editor(s): Shrikaant Kulkarni (Sanjivani University, India & Victorian Institute of Technology, Australia), Hemantkumar Akolkar (Rayat Shikshan Sanstha’s Abasaheb Marathe Arts and New Commerce Science College, India), Bapurao B. Shingate (Dr. Babasaheb Ambedkar Marathwada University, India)and Vijay M. Khedkar (Vishwakarma University, India)
DOI: 10.4018/979-8-3693-7267-8.ch007
Purchase
|
Abstract
Heterocyclic compounds play a crucial role in medicinal chemistry, serving as key components in the development of pharmacologically active molecules. The therapeutic promise of many synthesized drugs can be attributed to their heterocyclic scaffolds, wherein even minor modifications in the heterocyclic structure can significantly impact the drug's efficacy. Among these, benzimidazoles are particularly significant. These class of compounds comprises a combination of the aromatic benzene ring and an imidazole ring. A significant natural form of benzimidazole found in nature is N-ribosyl-dimethyl benzimidazole, which plays a crucial role in coordinating to the cobalt metal in vitamin B12. Extensive biochemical and pharmacological research has demonstrated that benzimidazoles are highly effective against various strains of microorganisms. Furthermore, they have exhibit a broad spectrum of biological activities, including anti-inflammatory, anticancer, antihistamine, antimicrobial, antifungal, antioxidant, antidiabetic and antiviral activities.
Related Content
|
Popat Mohite, Shubham Munde, Sudarshan Singh, Bhupendra Prajapati.
© 2026.
20 pages.
|
|
P. Selvakumar, S. Seenivasan, Sumanta Bhattacharya, D. Sudha, A. Akila, Manjunath T. C..
© 2026.
14 pages.
|
|
Nikita Patel, Miral Vora, Asha Joshi, Bhupesh Bhatt.
© 2026.
36 pages.
|
|
Bancha Yingngam.
© 2026.
74 pages.
|
|
Nandan Chamanlal Pomal, Keyur D. Bhatt, Ageetha Vanaamudan.
© 2026.
34 pages.
|
|
Keyur D. Bhatt, Nandan C. Pomal, Dhruvansh Patni, Nihal Patel.
© 2026.
30 pages.
|
|
Popat Mohite, Roshan Dave, Shubham Munde, Anil Raosaheb Pawar, Sudarshan Singh, Bhupendra Prajapati, Aarati Budhar.
© 2026.
32 pages.
|
|
|