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Quantitative Modeling of Neuronal Polarization
Abstract
Biological phenomena are systematically controlled by various components. In addition to biological molecules, physical components such as length and force must play an important role, especially in the cellular morphogenesis. Although a quantitative mathematical model is useful for understanding the underlying mechanism of biological phenomena, a model including the physical components is likely to become too complex to be designed mathematically. In the authors’ previous work, they proposed a quantitative mathematical model of neuronal polarization that is described by several simple equations and can reproduce a number of experimental observations. Based on that work, this chapter explains how the authors obtained a simple quantitative model from the complex processes of neuronal polarization.
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