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Application of Responsive Intelligent Biomaterials in Regenerative Medicine
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Author(s): Wenqiang Xie (Southern Medical University, China), Yuan Su (Southern Medical University, China), Ruiqi Zhang (Southern Medical University, China), Sijia Li (Foshan University, China), Jia Ni (Southern Medical University, China)and Longquan Shao (Southern Medical University, China)
Copyright: 2026
Pages: 18
Source title:
Biomedical Applications and Toxicity of Polymers, Nanoparticles, Biomaterials, and Metal Ions
Source Author(s)/Editor(s): Deniz Eren Erişen (Institute of Semiconductors, Guangdong Academy of Sciences, China), Faez Iqbal Khan (Xi’an Jiaotong-Liverpool University, China), Cheng Chang (Institute of New Materials, Guangdong Academy of Sciences, China & University of Birmingham, UK)and Kai-Cheng Yan (University of Bath, UK)
DOI: 10.4018/979-8-3373-0055-9.ch005
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Abstract
Responsive intelligent biomaterials, characterized by their ability to sense and respond to external or internal stimuli, have emerged as promising candidates in regenerative medicine (RM). RM aims to replace or regenerate damaged human cells, tissues, or organs to restore normal function. However, their mechanisms of action are not fully understood, especially at the molecular level. Studies on long-term stability, in vivo degradation, and tissue impact are lacking. Translation from research to clinical application faces challenges due to physiological and genetic differences between animal models and humans, and inadequate clinical data. This chapter summarizes the current applications of responsive intelligent biomaterials in RM, encompassing bone regeneration, cartilage regeneration, skin regeneration, nerve regeneration, and myocardial regeneration. This chapter aims to help overcome these hurdles and successfully apply responsive intelligent biomaterials in regenerative medicine.
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