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From Imaging to Drug Delivery and Treatment: Nano-Biomaterials for the Nervous System Disorders
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Author(s): Seyyed Mohammad Amin Mousavi-Sagharchi (Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran), Mahdieh Ranjbar-Jamalabadi (Isfahan University of Technology, Isfahan, Iran), Sama Yavari (Tabriz University, Iran), Elina Afrazeh (Khorramshahr University of Marine Science and Technology, Khorramshahr, Iran), Naresh Poondla (Icahn School of Medicine at Mount Sinai, New York, USA)and Mohsen Sheykhhasan (Cellular and Molecular Research Center, Qom University of Medical Sciences, Qom, Iran)
Copyright: 2026
Pages: 32
Source title:
Biomedical Applications and Toxicity of Polymers, Nanoparticles, Biomaterials, and Metal Ions
Source Author(s)/Editor(s): Deniz Eren Erişen (Institute of Semiconductors, Guangdong Academy of Sciences, China), Faez Iqbal Khan (Xi’an Jiaotong-Liverpool University, China), Cheng Chang (Institute of New Materials, Guangdong Academy of Sciences, China & University of Birmingham, UK)and Kai-Cheng Yan (University of Bath, UK)
DOI: 10.4018/979-8-3373-0055-9.ch004
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Abstract
Nano-sized particles, ranging from 1 to 100 nm, uniquely traverse blood vessels and cell membranes, making nano-biomaterials highly promising for treating brain and nervous system disorders. Their small size facilitates efficient drug delivery, enabling them to penetrate the blood-brain barrier as effective nanocarriers. Additionally, nanoparticles play a crucial role in diagnosing various conditions, especially neurological disorders, allowing for non-invasive imaging of the brain and nervous system. Nano-biomaterials can potentially mitigate the irreversible effects of conditions like Alzheimer's and Parkinson's diseases. Various types of nanomaterials, including metal-based nanoparticles (e.g., gold nanoparticles), carbon nanotubes, silicon nanoparticles, nanocrystals, nanodiscs, liposomes, micelles, and polymeric nanoparticles, are applicable to neurological disorders. This chapter aims to explore the applications of nano-biomaterials in the diagnosis and treatment of nervous system disorders, highlighting their innovative contributions to modern medicine.
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