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Microarray Data Mining

Microarray Data Mining

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Author(s): Li-Min Fu (Southern California University of Health Sciences, USA)
Copyright: 2009
Pages: 7
Source title: Encyclopedia of Data Warehousing and Mining, Second Edition
Source Author(s)/Editor(s): John Wang (Montclair State University, USA)
DOI: 10.4018/978-1-60566-010-3.ch190

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Abstract

Based on the concept of simultaneously studying the expression of a large number of genes, a DNA microarray is a chip on which numerous probes are placed for hybridization with a tissue sample. Biological complexity encoded by a deluge of microarray data is being translated into all sorts of computational, statistical or mathematical problems bearing on biological issues ranging from genetic control to signal transduction to metabolism. Microarray data mining is aimed to identify biologically significant genes and find patterns that reveal molecular network dynamics for reconstruction of genetic regulatory networks and pertinent metabolic pathways.

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