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Exploring the Role of Metal Ions in Modern Medicine From Antimicrobial Coatings to Diagnostic Imaging and Targeted Therapies
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Author(s): Hari Shankar Biswas (Surendranath College, India), Shib Shankar Biswas (Surendranath College, India), Amit Kr. Kundu (Sripat Singh College, India)and Dilip K. Maiti (University of Calcutta, India)
Copyright: 2026
Pages: 26
Source title:
Biomedical Applications and Toxicity of Polymers, Nanoparticles, Biomaterials, and Metal Ions
Source Author(s)/Editor(s): Deniz Eren Erişen (Institute of Semiconductors, Guangdong Academy of Sciences, China), Faez Iqbal Khan (Xi’an Jiaotong-Liverpool University, China), Cheng Chang (Institute of New Materials, Guangdong Academy of Sciences, China & University of Birmingham, UK)and Kai-Cheng Yan (University of Bath, UK)
DOI: 10.4018/979-8-3373-0055-9.ch012
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Abstract
Metal ions are vital in modern medicine, contributing to antimicrobial coatings, diagnostic imaging, and therapeutic treatments. This review explores their diverse roles, emphasizing biological interactions and clinical importance. Transition metals like gold, silver, copper, and zinc possess antimicrobial properties, while iron and gadolinium enhance imaging techniques, notably MRI. Platinum-based drugs like cisplatin are crucial in cancer chemotherapy, showcasing the therapeutic value of metal ions. The review discusses metal ion interactions with biological systems, focusing on roles as enzymatic cofactors, redox agents, and signaling molecules. Challenges such as toxicity, resistance, and environmental impact are also addressed. Advances in nanotechnology, biomaterials, and personalized medicine are driving the development of safer, more effective metal ion-based therapies. It highlights the importance of continued research to unlock the potential of metal ions in healthcare, paving the way for future innovations in antimicrobial, imaging, and targeted therapeutic applications.
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