The IRMA Community
Newsletters
Research IRM
Click a keyword to search titles using our InfoSci-OnDemand powered search:
|
Applications of Metabolic Flux Balancing in Medicine
|
|
Author(s): Ferda Mavituna (The University of Manchester, UK), Raul Munoz-Hernandez (The University of Manchester, UK)and Ana Katerine de Carvalho Lima Lobato (Federal University of Rio Grande do Norte, Brazil, and Potiguar University, Brazil)
Copyright: 2009
Pages: 17
Source title:
Handbook of Research on Systems Biology Applications in Medicine
Source Author(s)/Editor(s): Andriani Daskalaki (Max Planck Institute for Molecular Genetics, Germany)
DOI: 10.4018/978-1-60566-076-9.ch027
Purchase
|
Abstract
This chapter summarizes the fundamentals of metabolic flux balancing as a computational tool of metabolic engineering and systems biology. It also presents examples from the literature for its applications in medicine. These examples involve mainly liver metabolism and antibiotic production. Metabolic flux balancing is a computational method for the determination of metabolic pathway fluxes through a stoichiometric model of the cellular pathways, using mass balances for intracellular metabolites. It is a powerful tool to study metabolism under normal and abnormal conditions with a view to engineer the metabolism. Its extended potential in medicine is emphasized in the future trends.
Related Content
|
Saloua Mabsor-Zgandaoui, Khawla Rachmoune, Ilham Aftais, Fatima Ezzahra Elamrani, Imade Amradi, Adil El Housseini, Youssef Ait Hamdan, Youness Zgandaoui, Abdelghani Iddar, Mohammed El Mzibri, Adnane Moutaouakkil, Aboubaker El Hessni, Abdelhalim Mesfioui.
© 2026.
30 pages.
|
|
Yusuf Olatunji Waidi.
© 2026.
20 pages.
|
|
Ajinkya Nene, Sorour Sadeghzade, Wenjie Yang, Prakash Somani.
© 2026.
12 pages.
|
|
Seyyed Mohammad Amin Mousavi-Sagharchi, Mahdieh Ranjbar-Jamalabadi, Sama Yavari, Elina Afrazeh, Naresh Poondla, Mohsen Sheykhhasan.
© 2026.
32 pages.
|
|
Wenqiang Xie, Yuan Su, Ruiqi Zhang, Sijia Li, Jia Ni, Longquan Shao.
© 2026.
18 pages.
|
|
Zhengao Wang, Huiyu Zhao, Yao Han, Wuyi Zhou, Chengyun Ning.
© 2026.
30 pages.
|
|
Navya Aggarwal, Shinjini Sen, Tanmay J. Urs, Shreya Gupta, Banashree Bondhopadhyay.
© 2026.
36 pages.
|
|
|