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ROS in Precision Medicine in Neurological Diseases: Personalized Approaches
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Author(s): Yogesh Chaudhari (Department of Pharmaceutical Chemistry, Shri Vile Parle Kelavani Mandal's Institute of Pharmacy, Dhule, India), Nilesh Patil (Department of Pharmaceutical Chemistry, Shri Vile Parle Kelavani Mandal's Institute of Pharmacy, Dhule, India), Ansari Rashid (Department of Pharmacology, Shri Vile Parle Kelavani Mandal's Institute of Pharmacy, Dhule, India), Pawan Gupta (Department of Pharmaceutical Chemistry, Shri Vile Parle Kelavani Mandal's Institute of Pharmacy, Dhule, India), Rewati Wanjari (Department of Pharmaceutical Chemistry, Shri Vile Parle Kelavani Mandal's Institute of Pharmacy, Dhule, India)and Pranav Kumar Prabhakar (Lovely Professional University, India & Nagaland University, India)
Copyright: 2025
Pages: 32
Source title:
The Role of Reactive Oxygen Species in Human Health and Disease
Source Author(s)/Editor(s): Pranav Kumar Prabhakar (Department of Biotechnology, Nagaland University, India)
DOI: 10.4018/979-8-3693-7919-6.ch014
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Abstract
Reactive oxygen species (ROS), are a class of unstable chemicals produced by almost every subcellular organelle in cell. The ROS are highly reactive molecules that play essential roles in cell signaling and homeostasis but can also cause damage to cellular components when present in excess. The elevated levels of ROS, are causing damage to DNA, proteins, and lipids, promoting genetic instability, number of neurological illnesses, including, Alzheimer's, and Parkinson's disease. Precision medicine is an innovative approach to adapting medical treatment to the individual characteristics of each patient. This involves treating every patient as an individual and focusing on alternative healthcare treatment to every patient's unique characteristic. It relies on understanding how a person's genetic makeup, environment, and lifestyle affect their health and disease. The precision medicine enables early detection, prognostication, and monitoring of disease progression, allowing for timely and tailored interventions to mitigate ROS-mediated damage and improve patient outcomes.
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