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Liposome-Encapsulated Antimicrobial Peptides: Potential Infectious Diseases Therapy
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Author(s): Anju Gupta (Rose-Hulman Institute, USA), Reetu Gupta (South Coast Hospitals Group, USA)and Sudarshan Kurwardkar (California State University, USA)
Copyright: 2015
Pages: 32
Source title:
Handbook of Research on Diverse Applications of Nanotechnology in Biomedicine, Chemistry, and Engineering
Source Author(s)/Editor(s): Shivani Soni (Alabama State University, USA), Amandeep Salhotra (City of Hope National Medical Center, USA)and Mrutyunjay Suar (KIIT University, India)
DOI: 10.4018/978-1-4666-6363-3.ch014
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Abstract
The purpose of this chapter is to review the potential use of liposomes and peptides to address the ongoing challenges in infectious diseases involving antimicrobial resistance. The First section of this chapter describes and discusses the use of liposomes as model membrane to gain an insight on the membrane binding and disruption behavior of the potent peptides. Under this section, various biophysical techniques used to characterize the interactions are reviewed. In the second section, the use of antimicrobial peptides as an alternative to conventional antimicrobial therapy is presented. The final section of this chapter reviews liposomal encapsulation of antimicrobial peptides as an effective delivery strategy.
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