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Impact of Obesity on Cognitive Skills in Patients With Schizophrenia: Oxidative Mechanisms

Impact of Obesity on Cognitive Skills in Patients With Schizophrenia: Oxidative Mechanisms
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Author(s): Kadir Uludag (Shanghai Jiao Tong University Mental Health Center, China)and Ali Sabior (Poltava State Medical University, Ukraine)
Copyright: 2024
Pages: 15
Source title: Nutrition Controversies and Advances in Autoimmune Disease
Source Author(s)/Editor(s): Srikanta Patnaik (SOA University, India & Interscience Institute of Management and Technology, India), Ahmed M. Hamad (Benha University, Egypt), Debjyoti Paul (Amity University, Kolkata, India), Pushan Kumar Dutta (Amity University, Kolkata, India)and Muhammad Shafiq (Guangzhou University, China & Shenyang Normal University, China)
DOI: 10.4018/979-8-3693-5528-2.ch017

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Abstract

Previous literature has demonstrated that obesity is associated with cognitive deficits in various domains, including memory, attention, and working memory. In this manuscript, the authors have examined the effects of obesity on cognitive skills in patients with schizophrenia (SCZ), using inflammatory and oxidative approaches to explain the relationship between obesity and symptom severity. They conducted a literature search on PubMed using the keywords “obesity cognition schizophrenia symptoms.” The analysis revealed that obesity status was associated with cognitive impairments in SCZ patients, with increased body mass index (BMI) linked to reduced cognitive performance. However, only a few studies reported a positive relationship between increased cognitive skills and obesity status. Obesity, overweight status, and increasing BMI are linked to cognitive impairments in SCZ patients, particularly in domains such as memory, attention, and working memory.

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