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CT Imaging in Neurosurgical Interventions: Optimizing Seizure Management and Surgical Planning
Abstract
Traumatic Brain Injury (TBI) is a significant morbidity and mortality cause worldwide, and post-traumatic seizures (PTS) are a common and severe complication. TBI can be followed by early (within seven days of injury) or late-onset (beyond seven days) seizures, both of which are linked to neurological deterioration and poor patient prognosis. The Brain Trauma Foundation recommends anticonvulsants for the prophylaxis of early seizures. Its high bioavailability and low drug interactions were responsible for increased tolerability and long-term efficacy. Brivaracetam is a desirable choice for early seizure prophylaxis in TBI patients with greater efficacy and fewer adverse effects compared to traditional anticonvulsants. More large-scale randomized controlled trials are necessary to validate these findings and establish Brivaracetam as a standard of care in post-traumatic seizure management.
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