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An Intelligent Framework for Early Chronic Kidney Disease Prognosis: Hybrid Ensemble and Statistical Feature Selection Approach and Comparative Study

An Intelligent Framework for Early Chronic Kidney Disease Prognosis: Hybrid Ensemble and Statistical Feature Selection Approach and Comparative Study
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Author(s): Jayesh Motwani (Vellore Institute of Technology, India), Avinash Chandra (Vellore Institute of Technology, India), Nilamadhab Mishra (VIT Bhopal University, India), Anand Motwani (VIT Bhopal University, India)and Monica Arya (CMR Engineering College, Kandlakoya, India)
Copyright: 2026
Pages: 32
Source title: AI-Driven Strategies for Sustainable Guest Experience in Intelligent Hospitality
Source Author(s)/Editor(s): Ahmed K. Elnagar (Taibah University, Saudi Arabia), Abdelkader Mohamed Sghaier Derbali (Taibah University, Saudi Arabia)and Ahmad Mohammad Herzallah (Al-Quds University, Palestine)
DOI: 10.4018/979-8-3373-8197-8.ch013

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Abstract

We propose a hybrid wrapper approach, “Statistical-Recursive Feature Elimination” (S-RFE), to obtain an optimal and highly predictive subset of features. Max Voting Ensemble (MVE) optimization is applied to effectively predict diseases with optimal features, where the problem of finding the best classifier is formulated by representing multiple objective functions as a single objective function. Significant disease predictors were validated using statistical significance values and AUC-ROC. The proposed model has been experimentally validated for real data, and a comparison of models with different benchmark classifiers is also presented. We have achieved maximum accuracy (99.25%) and F1-score (99.2), with accuracy (0.99), having the ideal count of predictive features. Our prototype generates alerts for patients at risk, as well as for any new patients who may be at risk.

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