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Design Techniques for Microfluidic Devices Implementation Applicable to Chemical Analysis Systems: Theoretical and Experimental Analysis of Microcomponents
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Author(s): Reinaldo Lucas dos Santos Rosa (University of São Paulo, Brazil)and Antonio Carlos Seabra (University of São Paulo, Brazil)
Copyright: 2019
Pages: 28
Source title:
Process Analysis, Design, and Intensification in Microfluidics and Chemical Engineering
Source Author(s)/Editor(s): Harrson Silva Santana (University of Campinas, Brazil), João Lameu da Silva Jr (Federal Institute of Education, Science, and Technology of South of Minas Gerais, Brazil)and Osvaldir Pereira Taranto (University of Campinas, Brazil)
DOI: 10.4018/978-1-5225-7138-4.ch007
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Abstract
This chapter provides a guide for microfluidic devices development and optimization focused on chemical analysis applications, which includes medicine, biology, chemistry, and environmental monitoring, showing high-level performance associated with a specific functionality. Examples are chemical analysis, solid phase extraction, chromatography, immunoassay analysis, protein and DNA separation, cell sorting and manipulation, cellular biology, and mass spectrometry. In this chapter, most information is related to microfluidic devices design and fabrication used to perform several steps concerning chemical analysis, process preparation of reagents, samples reaction and detection, regarding water quality monitoring. These steps are especially relevant to lab-on-chip (LOC) and micro-total-analysis-systems (μTAS). μTAS devices are developed in order to simplify analytical chemist work, incorporating several analytical procedures into flow systems. In the case of miniaturized devices, the analysis time is reduced, and small volumes (nL) can be used.
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