The IRMA Community
Newsletters
Research IRM
Click a keyword to search titles using our InfoSci-OnDemand powered search:
|
Up-Converting Nanoparticles: Promising Markers for Biomedical Applications
Abstract
Up-converting nanoparticles are dielectric crystalline particles doped with rare-earth ions such as Yb3+, Er3+, Tm3+, Ho3+, Nd3+, etc. When excited in infrared, they emit visible radiation. Used as markers, they present significant advantages in comparison to traditional fluorophores: sharp emission lines, superior photostability, resistence to photobleaching, no blinking and lack of toxicity. Infrared radiation is less harmful to cells avoiding tissue degradation, minimizes auto-fluorescence from endogenous biocomponents offering a good signal-to-background ratio and penetrates tissues deeply. In spite of the great advantages of using up-converting nanoparticles for biomedical applications, there are still some limitations. These refer to identification of optimal size suited for specific samples, prevention of aggregation, water stability/dispersibility, optical efficiency and biocompatibility. This chapter reviews principal characteristics of up-converting nanoparticles and issues related to their use in biomedical applications.
Related Content
|
David Edson Ribeiro, Valter Augusto de Freitas Barbosa, Clarisse Lins de Lima, Ricardo Emmanuel de Souza, Wellington Pinheiro dos Santos.
© 2021.
15 pages.
|
|
Juliana Carneiro Gomes, Maíra Araújo de Santana, Clarisse Lins de Lima, Ricardo Emmanuel de Souza, Wellington Pinheiro dos Santos.
© 2021.
12 pages.
|
|
Maíra Araújo de Santana, Jessiane Mônica Silva Pereira, Clarisse Lins de Lima, Maria Beatriz Jacinto de Almeida, José Filipe Silva de Andrade, Thifany Ketuli Silva de Souza, Rita de Cássia Fernandes de Lima, Wellington Pinheiro dos Santos.
© 2021.
19 pages.
|
|
Jessiane Mônica Silva Pereira, Maíra Araújo de Santana, Clarisse Lins de Lima, Rita de Cássia Fernandes de Lima, Sidney Marlon Lopes de Lima, Wellington Pinheiro dos Santos.
© 2021.
25 pages.
|
|
Adriel dos Santos Araujo, Roger Resmini, Maira Beatriz Hernandez Moran, Milena Henriques de Sousa Issa, Aura Conci.
© 2021.
35 pages.
|
|
Abir Baâzaoui, Walid Barhoumi.
© 2021.
21 pages.
|
|
Marcus Costa de Araújo, Luciete Alves Bezerra, Kamila Fernanda Ferreira da Cunha Queiroz, Nadja A. Espíndola, Ladjane Coelho dos Santos, Francisco George S. Santos, Rita de Cássia Fernandes de Lima.
© 2021.
44 pages.
|
|
|