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Role of Reactive Oxygen Species in Cellular Signalling: Insights Into Pathological Processes and Therapeutic Strategies
Abstract
ROS are molecules of the cell signalling, produced during oxidative metabolism and causes various human disease as its accumulation leads to deregulation of antioxidant defence mechanism (Wang et al. 2021). ROS regulates several cell signalling pathways which are responsible for apoptosis, survival of the cell, growth and maintenance of metabolic activities of the cell. This chapter focuses on the role of reactive oxygen species in cell signalling. Cell signalling is the process through which cell communicate each other and responds to environment and stimuli through a cascade of events, ultimately leading to production of desired protein as a result. Therefore, a comprehensive understanding of mechanism of cell signalling enhances our knowledge of intrinsic cellular process and also provide insight for development therapeutic strategies for curing various diseases.
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