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Role of Herbal Medicine/Phyto-Therapy in Cancer Prevention by Inhibiting Epithelial-Mesenchymal Transition (EMT) Pathways

Role of Herbal Medicine/Phyto-Therapy in Cancer Prevention by Inhibiting Epithelial-Mesenchymal Transition (EMT) Pathways
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Author(s): Rekha Gahtori (Department of Biotechnology, Bhimtal Campus, Kumaun University, India) and Ashutosh Paliwal (Department of Biotechnology, Bhimtal Campus, Kumaun University, Nainital, India)
Copyright: 2021
Pages: 20
Source title: Treating Endocrine and Metabolic Disorders With Herbal Medicines
Source Author(s)/Editor(s): Arif Hussain (Manipal Academy of Higher Education, UAE) and Shalini Behl (Manipal Academy of Higher Education, UAE)
DOI: 10.4018/978-1-7998-4808-0.ch009

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Abstract

Human life is surrounded and dependent on its environment. Human civilization is nurtured by nature as it provides raw materials that are used in the manufacturing of various essential products like medicine, food items, etc. Not only developing countries but developed countries also depend on herbal-based medications. Cancer is a global health burden. Epithelial-mesenchymal-transition (EMT) plays a key role in cancer progression and is also stimulated by different extracellular signals and could be regulated at different levels. Conventional therapies exhibit a cytotoxic effect, which encourages the development of a new approach that could be used with synthetic drugs. Phytotherapy emerged as an effective weapon against cancer. Herbal drugs directly target different signaling pathways that promote EMT and eventually lead to cancer.

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