The IRMA Community
Newsletters
Research IRM
Click a keyword to search titles using our InfoSci-OnDemand powered search:
|
The Role of Genetic Data Analysis for Precision Therapy in Cancer: Personalized Medicine Concept in Cancer Treatment
|
|
Author(s): Sunishtha Singh Yadav (Amity Institute of Biotechnology, Amity University, India), Vandana Chauhan (Amity Institute of Biotechnology, Amity University, India), Vijeta Singh (Amity Institute of Biotechnology, Amity University, India)and Svenja Kohler (University of Lübeck, Germany)
Copyright: 2024
Pages: 17
Source title:
Research Anthology on Bioinformatics, Genomics, and Computational Biology
Source Author(s)/Editor(s): Information Resources Management Association (USA)
DOI: 10.4018/979-8-3693-3026-5.ch067
Purchase
|
Abstract
Cancer has been known as a devastating disease that takes thousands of lives every year. And since this is a heterogenous disease, standard treatments, like chemotherapy, radiation, and chemo-radio therapy, are effective in specific patient population subset only. Genetic differences play a very crucial role in defining cancer susceptibility and also in determining the drug's efficacy by affecting regulation, expression, and activity of drug metabolizing enzymes, drug transporters, and drug receptors. This genetic variability of the disease lends itself to the emerging field of precision or personalized medicine. There are some specific ways of acquiring data for precision or personalized medicine approach like genome wide association scan (GWAS). This is basically identification and scanning of biomarkers throughout the complete DNA/genome of several individuals to study any type of genetic variations which are linked with any form of cancer.
Related Content
|
Alessandra Lima da Silva, Diego Mariano, Mariana Parise, Angie L. A. Puelles, Tatiane Senna Bialves, Luana Luiza Bastos, Lucas Santos, Rafael Pereira Lemos.
© 2025.
22 pages.
|
|
Seyyed Mohammad Amin Mousavi Sagharchi, Mohsen Sheykhhasan, Atousa Ghorbani, Elina Afrazeh, Naresh Poondla, Naser Kalhor, Hamid Tanzadehpanah, Hanie Mahaki, Hamed Manoochehri.
© 2025.
46 pages.
|
|
Eduarda Guimarães Sousa, Lucas Gabriel Rodrigues Gomes, Fernanda Diniz Prates, Talita Pereira Gomes, Gabriel Camargos Gomes, Janaíne Aparecida de Paula, Ana Lua de Oliveira Vinhal, Bernardo Buhr Alves Mendonça, Mariana Letícia Costa Pedrosa, Luiza Pereira Reis, Aline Ferreira Maciel de Oliveira, Marcus Vinicius Canário Viana, Arun Kumar Jaiswal, Siomar de Castro Soares, Vasco Ariston de Carvalho Azevedo.
© 2025.
38 pages.
|
|
Diego Mariano, Lucas Moraes dos Santos, Raquel Cardoso de Melo-Minardi.
© 2025.
30 pages.
|
|
Alessandra G. Cioletti, Frederico C. Carvalho, Lucas M. Dos Santos, Raquel C. M. Minardi.
© 2025.
32 pages.
|
|
Leandro Morais de Oliveira, Luana Luiza Bastos, Vivian Morais Paixão, Leticia Aparecida Gontijo, Tatiane Senna Bialves, Diego Mariano, Raquel Cardoso de Melo Minardi.
© 2025.
40 pages.
|
|
Angie Atoche Puelles, Luana Luiza Bastos, Vivian Morais Paixão, Sheila Cruz Araujo, Raquel Cardoso de Melo Minardi.
© 2025.
28 pages.
|
|
|