The IRMA Community
Newsletters
Research IRM
Click a keyword to search titles using our InfoSci-OnDemand powered search:
|
Prediction of Compound-protein Interactions with Machine Learning Methods
Abstract
In silico prediction of compound-protein interactions from heterogeneous biological data is critical in the process of drug development. In this chapter the authors review several supervised machine learning methods to predict unknown compound-protein interactions from chemical structure and genomic sequence information simultaneously. The authors review several kernel-based algorithms from two different viewpoints: binary classification and dimension reduction. In the results, they demonstrate the usefulness of the methods on the prediction of drug-target interactions and ligand-protein interactions from chemical structure data and genomic sequence data.
Related Content
|
Bhargav Naidu Matcha, Sivakumar Sivanesan, K. C. Ng, Se Yong Eh Noum, Aman Sharma.
© 2023.
60 pages.
|
|
Lavanya Sendhilvel, Kush Diwakar Desai, Simran Adake, Rachit Bisaria, Hemang Ghanshyambhai Vekariya.
© 2023.
15 pages.
|
|
Jayanthi Ganapathy, Purushothaman R., Ramya M., Joselyn Diana C..
© 2023.
14 pages.
|
|
Prince Rajak, Anjali Sagar Jangde, Govind P. Gupta.
© 2023.
14 pages.
|
|
Mustafa Eren Akpınar.
© 2023.
9 pages.
|
|
Sreekantha Desai Karanam, Krithin M., R. V. Kulkarni.
© 2023.
34 pages.
|
|
Omprakash Nayak, Tejaswini Pallapothala, Govind P. Gupta.
© 2023.
19 pages.
|
|
|