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Parkinson's Disease: A Progressive Disorder of the Nervous System That Affects Movement

Parkinson's Disease: A Progressive Disorder of the Nervous System That Affects Movement
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Author(s): Vaibhav Walia (Maharshi Dayanand University, India), Ashish Gakkhar (Maharshi Dayanand University, India)and Munish Garg (Maharshi Dayanand University, India)
Copyright: 2019
Pages: 22
Source title: Handbook of Research on Critical Examinations of Neurodegenerative Disorders
Source Author(s)/Editor(s): Md. Sahab Uddin (Southeast University, Bangladesh)and Md. Shah Amran (University of Dhaka, Bangladesh)
DOI: 10.4018/978-1-5225-5282-6.ch012

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Abstract

Parkinson's disease (PD) is a neurodegenerative disorder in which a progressive loss of the dopaminergic neurons occurs. The loss of the neurons is most prominent in the substantia nigra region of the brain. The prevalence of PD is much greater among the older patients suggesting the risk of PD increases with the increase of age. The exact cause of the neurodegeneration in PD is not known. In this chapter, the authors introduce PD, demonstrate its history, pathogenesis, neurobiology, sign and symptoms, diagnosis, and pharmacotherapy.

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