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Neurotoxicity and Biosafety of Nanomaterials

Neurotoxicity and Biosafety of Nanomaterials
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Author(s): Shadi Askari (Amirkabir University of Technology, Iran)and Mahnaz Eskandari (Amirkabir University of Technology, Iran)
Copyright: 2025
Pages: 26
Source title: Nanomaterials and the Nervous System
Source Author(s)/Editor(s): Deniz Eren Erisen (Nanjing University of Aeronautics and Astronautics, China), Kadir Uludag (Shanghai Jiao Tong University, China)and Nafees Ahmad (Central South University, China)
DOI: 10.4018/979-8-3693-3065-4.ch001

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Abstract

This chapter explores the neurotoxicity of nanomaterials, focusing on their potential to induce harmful effects on the central nervous system. Nanomaterials, with dimensions between 1 and 100 nanometers, possess unique properties that make them valuable in various industries. However, their ability to penetrate the brain through different pathways raises concerns about neurotoxicity. Studies have highlighted the adverse effects of nanomaterial exposure, including oxidative stress, inflammation, and gene expression alterations. Understanding the mechanisms and factors influencing nanomaterial neurotoxicity is crucial for ensuring their safe use across diverse applications.

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