Neurodegenerative Disorders: An Introduction

View Sample PDF

Author(s): Mohamed M. Amin (National Research Centre, Egypt)
Copyright: 2019
Pages: 22
Source title: Handbook of Research on Critical Examinations of Neurodegenerative Disorders
Source Author(s)/Editor(s): Md. Sahab Uddin (Southeast University, Bangladesh)and Md. Shah Amran (University of Dhaka, Bangladesh)
DOI: 10.4018/978-1-5225-5282-6.ch009

Keywords: Medical Diagnosis and Practice / Medical Information Science Reference / Medicine & Healthcare / Neuroscience

Purchase

View Neurodegenerative Disorders: An Introduction on the publisher's website for pricing and purchasing information.

Abstract

Neurodegenerative diseases (NDs) are characterized by specific dysfunction and damage of neurons related to pathologically changed proteins that deposit in the patient brain but also in peripheral organs. These proteins can be used for therapy or used as biomarkers. Except for a plethora of alterations revealed for dissimilar neurodegeneration-related proteins, amyloid-β, prion protein, TAR DNA-binding protein 43 (TDP-43, transactive response DNA binding protein 43 kDa), tau and α-synuclein, or fused in sarcoma protein (FUS), molecular classification of NDs depend on the full morphological assessment of protein deposits, their spreading in the brain, and their correspondence to clinical signs with specific genetic modifications. The current chapter represents the etiology of neurodegeneration, classification of NDs, concentrating on the maximum applicable biochemical and anatomical characteristics and most imperative NDs.

The IRMA Community

Research IRM

Neurodegenerative Disorders: An Introduction

Purchase

Abstract

Related Content

IRMA Sponsors