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Nature's Warriors: Terpenes for Management of Prostate Cancer
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Author(s): Devender Singh (Guru Gobind Singh College of Pharmacy, India), Pardeep Kumar Mehla (Guru Gobind Singh College of Pharmacy, India), Bharat Bhushan Bahmani (Guru Gobind Singh College of Pharmacy, India), Anil Kumar (Guru Gobind Singh College of Pharmacy, India)and Hitesh Malhotra (Guru Gobind Singh College of Pharmacy, India)
Copyright: 2025
Pages: 34
Source title:
Analyzing Terpenes' Role in Cancer Treatment
Source Author(s)/Editor(s): Bhawna Chopra (Guru Gobind Singh College of Pharmacy, India), Ashwani Kumar Dhingra (Global Research Institute of Pharmacy, India), Priyanka Kriplani (Guru Gobind Singh College of Pharmacy, India)and Ritu Ojha (Cathay General Hospital, Taiwan)
DOI: 10.4018/979-8-3693-6972-2.ch005
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Abstract
Prostate cancer is a hormone-related neoplastic diseases with the highest mortality rate globally. Cancer cells are becoming resistant to chemotherapeutic agents, resulting in an urgent need for novel therapeutic compounds or alternatives to treat cancer. Phytochemicals could provide one of the most effective ways of controlling cancer through chemoprevention. A number of natural bioactive phytoconstituents including polyphenols, terpenoids, taxanes, and alkaloids showed their activity against prostate cancer. Based on several studies of clinical and epidemiological research, consuming a diet rich in terpenoid compounds lowers the risk of prostate cancer. Terpenoids may be the greatest remedy for treating prostate cancer because of their structural resemblance to human hormones, ability to halt the proliferation of tumor cells, and ability to eradicate them by blocking a number of cancer-specific targets such as the NF-κB, proteasome, and Bcl-2 (an anti-apoptotic protein). The chapter describes the role of various terpenoids in the treatment of prostate cancer.
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