Impact of Dietary Antioxidants on Redox Homeostasis and Its Effects on Health and Disease

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Author(s): Reyed M. Reyed (Genetic Engineering and Biotechnology Research Institute (GEBRI) & City of Scientific Research and Technological Applications, Egypt)and P. K. Prabhakar (Lovely Professional University, India & Nagaland University, India)
Copyright: 2025
Pages: 56
Source title: The Role of Reactive Oxygen Species in Human Health and Disease
Source Author(s)/Editor(s): Pranav Kumar Prabhakar (Department of Biotechnology, Nagaland University, India)
DOI: 10.4018/979-8-3693-7919-6.ch003

Keywords: Healthcare Administration / Medical Diagnosis and Practice / Medical Information Science Reference / Medicine & Healthcare

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Abstract

This chapter discusses the roles of reactive oxygen species (ROS) in cells, including their role in oxidative stress and redox balance. It explores how dietary antioxidants affect redox homeostasis, their sources, mechanisms of action, and antioxidant capacity. The chapter also discusses how antioxidants affect ROS-mediated signaling cascades and endogenous antioxidant defense mechanisms. It discusses the use of antioxidants in pharmacological approaches to treat chronic illnesses like cancer, neurological disorders, and cardiometabolic diseases. It also addresses the antioxidant paradox, where excessive antioxidant supplementation can disrupt redox equilibrium, emphasizing the importance of balancing pro- and antioxidative forces.

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Impact of Dietary Antioxidants on Redox Homeostasis and Its Effects on Health and Disease

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