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Exploring the Potential of Chitosan-Polydopamine Nanocomposites for Neural Tissue Regeneration

Exploring the Potential of Chitosan-Polydopamine Nanocomposites for Neural Tissue Regeneration
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Author(s): Deniz Eren Erisen (Nanjing University of Aeronautics and Astronautics, China)
Copyright: 2025
Pages: 14
Source title: Nanomaterials and the Nervous System
Source Author(s)/Editor(s): Deniz Eren Erisen (Nanjing University of Aeronautics and Astronautics, China), Kadir Uludag (Shanghai Jiao Tong University, China)and Nafees Ahmad (Central South University, China)
DOI: 10.4018/979-8-3693-3065-4.ch011

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Abstract

The chapter discusses the optimization of the physical and chemical properties of these nanocomposites to enhance their suitability for neural applications, such as tuning the surface chemistry to improve cell-material interactions and modifying the mechanical properties to match those of the native neural tissue. It also highlights the importance of rigorous in vitro and in vivo testing to evaluate the material's performance in supporting neural cell viability, differentiation, and integration with host tissue. The potential implications of this research are far-reaching, contributing not only to the advancement of neural tissue engineering but also to the broader scope of regenerative medicine. The chapter concludes with a discussion on the prospects of Chi-PDA nanocomposites in the development of next-generation neural interfaces, implants, and scaffolds, and their potential to significantly improve the quality of life for individuals with neural damage or degenerative conditions.

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