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Effect of Age on Heart Rate Variability Analysis in Breast Cancer Patients: Heart Rate Variability in Breast Cancer
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Author(s): Reema Shyamsunder Shukla (Birla Institute of Technology, India), Yogender Aggarwal (Birla Institute of Technology, India), Rakesh Kumar Sinha (Birla Institute of Technology, India)and Shreeniwas S. Raut (HCG Abdur Razzaque Ansari Cancer Center, India)
Copyright: 2020
Pages: 27
Source title:
Biomedical and Clinical Engineering for Healthcare Advancement
Source Author(s)/Editor(s): N. Sriraam (Ramaiah Institute of Technology, India)
DOI: 10.4018/978-1-7998-0326-3.ch008
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Abstract
Breast Cancer (BC) is the leading cause of death in women, worldwide. The Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) of BC can be studied using HRV measures. The main purpose of this chapter is to give an insight to clinicians via HRV measures with respect to age to make them understand the PS of patients. Data from 114 BC patients was segregated into two age groups, G1 (20 to 40 years) and G2 (41 to 75 years). The 5-minute electrocardiogram of the subjects was taken and HRV measures were extracted. One-way ANOVA with Posthoc Tukeys' HSD test was done. Triangular Index, Ratio of standard deviation of poincare plot perpendicular to the line of identity to the standard deviation along line of identity, Detrended Fluctuation Analysis descriptors, Approximate Entropy, Sample Entropy and Correlation Dimension significantly decreased from ECOG0 to 4 and from G1 to G2. The sympathetic activity increased with vagal withdrawal as age advanced.
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