Cancer and Signaling Pathway Deregulation

View Sample PDF

Author(s): Yingchun Liu (Dana-Farber Cancer Institute and Harvard Medical School, USA)
Copyright: 2011
Pages: 11
Source title: Handbook of Research on Computational and Systems Biology: Interdisciplinary Applications
Source Author(s)/Editor(s): Limin Angela Liu (Shanghai Jiao Tong University, China), Dongqing Wei (Shanghai Jiao Tong University, China), Yixue Li (Shanghai Jiao Tong University, China)and Huimin Lei (Shanghai Jiao Tong University, China)
DOI: 10.4018/978-1-60960-491-2.ch017

Keywords: Biologically-Inspired Computing / Biotechnology and Bioinformatics / Engineering Science Reference / Medicine & Healthcare

Purchase

View Cancer and Signaling Pathway Deregulation on the publisher's website for pricing and purchasing information.

Abstract

Cancer is a complex disease that is associated with a variety of genetic aberrations. The diagnosis and treatment of cancer have been difficult because of poor understanding of cancer and lack of effective cancer therapies. Many studies have investigated cancer from different perspectives. It remains unclear what molecular mechanisms have triggered and sustained the transition of normal cells to malignant tumor cells in cancer patients. This chapter gives an introduction to the genetic aberrations associated with cancer and a brief view of the topics key to decode cancer, from identifying clinically relevant cancer subtypes to uncovering the pathways deregulated in particular subtypes of cancer.

The IRMA Community

Research IRM

Cancer and Signaling Pathway Deregulation

Purchase

Abstract

Related Content

IRMA Sponsors