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Analysis of Neurotoxic Effects on the Nervous System Induced by Nanoparticles
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Author(s): Amadu Kayode Salau (Federal University of Health Sciences, Ila-Orangun, Nigeria), Muhammad Suleiman Shehu (Federal University of Health Sciences, Ila-Orangun, Nigeria), Sodiq Oluwaseun Dada (Federal University of Health Sciences, Ila-Orangun, Nigeria), Taiwo Ayodeji Sorunke (Federal University of Health Sciences, Ila-Orangun, Nigeria)and Adenike Temidayo Oladiji (University of Ilorin, Nigeria)
Copyright: 2025
Pages: 42
Source title:
Nanomaterials and the Nervous System
Source Author(s)/Editor(s): Deniz Eren Erisen (Nanjing University of Aeronautics and Astronautics, China), Kadir Uludag (Shanghai Jiao Tong University, China)and Nafees Ahmad (Central South University, China)
DOI: 10.4018/979-8-3693-3065-4.ch004
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Abstract
Nanomaterials, with their unique physical and chemical properties, have attracted much interest across various industries. However, their potential to traverse biological barriers and interact with the delicate nervous system raises concerns about neurotoxicity. This chapter explores the mechanisms of nanomaterial-induced neurotoxicity, highlighting the vulnerability of the nervous system and the potential routes of exposure. It provides an overview of established methodologies for assessing neurotoxicity, presents case studies, and experimental findings that underline the importance of rigorous evaluation. Strategies for safer nanomaterial development, including surface modification and biogenic fabrication are discussed. Additionally, the chapter emphasizes the need for robust regulatory frameworks and international collaboration to ensure the responsible development and application of nanomaterials, particularly in the discipline of nanomedicine.
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