Pathway Resources at the Rat Genome Database: A Dynamic Platform for Integrating Gene, Pathway and Disease Information

View Sample PDF

Author(s): Victoria Petri (Medical College of Wisconsin, USA)
Copyright: 2011
Pages: 21
Source title: Handbook of Research on Computational and Systems Biology: Interdisciplinary Applications
Source Author(s)/Editor(s): Limin Angela Liu (Shanghai Jiao Tong University, China), Dongqing Wei (Shanghai Jiao Tong University, China), Yixue Li (Shanghai Jiao Tong University, China)and Huimin Lei (Shanghai Jiao Tong University, China)
DOI: 10.4018/978-1-60960-491-2.ch014

Keywords: Bioinformatics / Biologically-Inspired Computing / Medical Information Science Reference / Medicine & Healthcare

Purchase

View Pathway Resources at the Rat Genome Database: A Dynamic Platform for Integrating Gene, Pathway and Disease Information on the publisher's website for pricing and purchasing information.

Abstract

The set of interacting molecules representing a biological pathway or network is a central concept in biology. It is within the pathway context that the functioning of individual molecules acquires purpose and it is the integration of these molecular circuitries that underlies the functioning of biological systems. In order to provide the research community with a dynamic platform for accessing pathway information, the Rat Genome Database (RGD – http://rgd.mcw.edu) is using a multi-tiered approach. In this chapter, the pathway resources that RGD currently offers are presented. Issues covered include: the biological pathway, the concept and the ontology, pathway literature curation and annotation of genes, interactive pathway diagrams, and tools and resources to access and navigate between pathway data. A case study is presented; future directions are discussed.

The IRMA Community

Research IRM

Pathway Resources at the Rat Genome Database: A Dynamic Platform for Integrating Gene, Pathway and Disease Information

Purchase

Abstract

Related Content

IRMA Sponsors