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Monocytes as Targets for Cancer Therapies
Abstract
The importance of monocytes in modulating the lymphocyte dependent tumor necrosis is a target for cancer therapeutics. Monocytes produce a plethora of chemokine receptors. Lymphocyte to monocyte ratio is one of the negative factors in cancer patients. It is being targeted for treatment of abnormal lymphocytopenia and monocytosis in untreatable metastatic cancer patients. The aim of the chapter is to throw light on the circadian and psychological factors that modulate the progression of cancer and identify novel targets for controlling transformation of preneoplasms to neoplasms, invasiveness, and metastasis.
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